The Fuchs Endothelial Corneal Dystrophy market report provides current treatment practices, emerging drugs, Fuchs Endothelial Corneal Dystrophy market share of the individual therapies, current and forecasted Fuchs Endothelial Corneal Dystrophy market Size from 2019 to 2032 segmented by seven major markets. The Report also covers current Fuchs Endothelial Corneal Dystrophy treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the Fuchs Endothelial Corneal Dystrophy market.
Key takeaways from the Fuchs Endothelial Corneal Dystrophy Market Research Report
- The increase in Fuchs Endothelial Corneal Dystrophy market size is a direct consequence of expected approval of emerging therapies and improved understanding and growing awareness of Fuchs Endothelial Corneal Dystrophy in the 7MM.
- According to DelveInsight’s analysis, FECD is more prominent in females in comparison to males.
- Fuchs Endothelial Corneal Dystrophy Market Companies are working such as Kowa Pharmaceuticals, Trefoil Therapeutics, ProQR Therapeutics, Emmecell, and others.
- Fuchs Endothelial Corneal Dystrophy Pipeline therapies such as Ripasudil (K-321), TTHX 1114, STN1010904/AE-001, EO2002, and others
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Fuchs Endothelial Corneal Dystrophy Overview
Fuchs endothelial corneal dystrophy is the most common form of corneal dystrophy. It is an inherited condition caused by changes in various genes, which lead to the abnormal function of the innermost layer of the cornea, the endothelium. The endothelium is made up of a single layer of cells (endothelial cells) which rest on a thin membrane (Descemet’s membrane). Endothelial cells normally function to keep the cornea clear and transparent by pumping fluid out of the stroma (the thick middle layer of the cornea). A small number of endothelial cells are normally lost when a person gets older but in Fuchs dystrophy this process is accelerated, causing the cornea to swell and become cloudy (corneal oedema), which in turn makes vision blurry. Most patients do not experience any symptoms when the first sign of Fuchs dystrophy is detected (known as corneal guttata), often by an optician during a routine eye check.
Recent Developmental Activities in the Fuchs Endothelial Corneal Dystrophy Market
- TTHX1114 has been shown in preclinical studies to stimulate endothelial cell proliferation and migration, and drive regeneration of the corneal endothelial layer. In addition to the trial in patients undergoing DSO surgery, the company is conducting a Phase 1/2 trial (“INTREPID”) to evaluate TTHX1114’s safety and ability to stimulate the regeneration of corneal endothelial cells lost due to corneal endothelial disorders, including FECD.
- Ripasudil hydrochloride hydrate is a rho-kinase inhibitor, it has been suggested that the compound may also act on other kinases in the eye, leading to investigations of its applicability to other ophthalmic diseases. As part of these efforts, development of the compound as a treatment for Fuchs endothelial corneal dystrophy (FECD) is underway.
Fuchs Endothelial Corneal Dystrophy Epidemiology Segmentation in the 7MM
- Total Fuchs endothelial corneal dystrophy Prevalent Cases
- Fuchs endothelial corneal dystrophy Gender-specific Cases
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Fuchs Endothelial Corneal dystrophy Treatment Market
FECD is slowly progressive, and typically patients do not seek treatment until the endothelial layer is badly degenerated. Transplantation is the only current treatment and there are no FDA-approved pharmacological therapies available for FECD. The early treatment is usually in the form of hypertonic saline eye drops or ointments that stabilizes or improve vision by drawing extra water out of the cornea. Other supportive treatments and surgical procedures such as phototherapeutic keratectomy, amniotic membrane transplants, anterior stromal puncture, and conjunctival flaps can be used to relieve painful symptoms, especially those associated with ruptured bullae in later stages of the disease. More recent approach to manage is the topical use of a ROCK inhibitor to speed up recovery and increase endothelial cell density than happens with DSO alone. Rhopressa is used as an off-label usage for FECD.
Fuchs Endothelial Corneal dystrophy Emerging Therapies
- Ripasudil (K-321)
- TTHX1114
- STN1010904/AE-001
- EO2002
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Scope of the Fuchs Endothelial Corneal dystrophy Market Research Report
- Coverage- 7MM
- Study Period- 2019-2032
- Forecast Period- 2022-2032
- Fuchs Endothelial Corneal Dystrophy Market Companies- Kowa Pharmaceuticals, Trefoil Therapeutics, ProQR Therapeutics, Emmecell, and others.
- Fuchs Endothelial Corneal Dystrophy Pipeline therapies- Ripasudil (K-321), TTHX 1114, STN1010904/AE-001, EO2002, and others
- Fuchs Endothelial Corneal Dystrophy Market Barriers and Drivers
- Fuchs Endothelial Corneal Dystrophy Unmet Needs
Table of Content
1. Key Insights
2. Executive Summary of Fuchs Endothelial Corneal Dystrophy (FECD)
3. Competitive Intelligence Analysis for Fuchs Endothelial Corneal Dystrophy (FECD)
4. Fuchs Endothelial Corneal Dystrophy (FECD): Market Overview at a Glance
5. Fuchs Endothelial Corneal Dystrophy (FECD): Disease Background and Overview
6. Patient Journey
7. Fuchs Endothelial Corneal Dystrophy (FECD) Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Fuchs Endothelial Corneal Dystrophy (FECD) Unmet Needs
10. Key Endpoints of Fuchs Endothelial Corneal Dystrophy (FECD) Treatment
11. Fuchs Endothelial Corneal Dystrophy (FECD) Marketed Products
12. Fuchs Endothelial Corneal Dystrophy (FECD) Emerging Therapies
13. Fuchs Endothelial Corneal Dystrophy (FECD): Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of Fuchs Endothelial Corneal Dystrophy (FECD)
17. KOL Views
18. Fuchs Endothelial Corneal Dystrophy Market Drivers
19. Fuchs Endothelial Corneal Dystrophy Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight
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