DelveInsight’s, “Metastatic Prostate Cancer Pipeline Insights, 2023” report provides comprehensive insights about 90+ companies and 110+ pipeline drugs in the metastatic prostate cancer pipeline landscape. It covers the Metastatic Prostate Cancer pipeline drug profiles, including Metastatic Prostate Cancer clinical trials and nonclinical stage products. It also covers the Metastatic Prostate Cancer therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
To explore more information on the latest breakthroughs in the Metastatic Prostate Cancer Pipeline treatment landscape of the report, click here @ Metastatic Prostate Cancer Pipeline Outlook
Metastatic Prostate Cancer Overview
Metastatic Prostate Cancer is a type of prostate cancer which spreads to the other parts of body, i.e., cancer has “metastasized.” Most often, prostate cancer spreads to the bones or lymph nodes. It’s also common for it to spread to the liver or lungs. It’s rarer for it to move to other organs, such as the brain. Metastatic prostate cancer is an advanced form of cancer. There’s no cure, but it can treat it and control it. Most men with advanced prostate cancer live a normal life for many years.
Key Takeaways from the Metastatic Prostate Cancer Pipeline Report
- Over 90+ Metastatic Prostate Cancer companies are evaluating 110+ Metastatic Prostate Cancer pipeline therapies in various stages of development, and their anticipated acceptance in the Metastatic Prostate Cancer market would significantly increase market revenue.
- The leading Metastatic Prostate Cancer Companies include Zenith Epigenetics, WntResearch, Veru Inc., VasGene Therapeutics, ValiRx, Vaccitech, Ultimovacs ASA, Trovagene, Tracon, Tmunity Therapeutics, Tesaro, Telix Pharmaceuticals, Taiho Pharmaceutical, Suzhou Kintor Pharmaceutical, Sotio, SeleXel, Roche, Regeneron Pharmaceuticals/Sanofi, Progenics Pharmaceuticals, Inc., Poseida Therapeutics, Pfizer Inc, Orion Corporation, Orion Pharma, ORIC Pharmaceuticals, OPKO Renal/Vifor Fresenius, OncoMax, Oncology Venture, Novartis, NewLink Genetics, Nerviano Medical Sciences, Nektar Therapeutics, Myovant Biosciences, Modra Pharmaceuticals, Minneamrita Therapeutics, Merck Sharp & Dohme Corp. Medivation, MedImmune, Madison Vaccines, Inc, Laekna Therapeutics Shanghai Co. Ltd., Karyopharm Therapeutics, Kangpu Biopharmaceuticals, Jiangsu HengRui Medicine Co., Ltd., Janssen Research & Development, LLC, Inovio Pharmaceuticals, Innocrin Pharmaceutical, Inhibitor Therapeutics, Inc., Immunomedics, Hinova Pharmaceuticals USA, Inc., Harpoon Therapeutics, Gilead, Genzada Pharmaceuticals, Genentech, Fortis Therapeutics, Foresee Pharmaceuticals, Five Eleven Pharma, ESSA Pharma, Epizyme Inc., Eli Lilly and Company, Effector Therapeutics, DexTech Medical, Corcept Therapeutics, Constellation Pharmaceuticals, Cleveland BioLabs, CellCentric, Celgene, Cancer Targeted Technology, Bristol Myers Squibb, Bristol Myers Squibb, Boehringer Ingelheim, BioNTech SE, Bellicum Pharmaceuticals, Beigene, Bayer, Bavarian Nordic, AstraZeneca plc, Astellas Pharmaceuticals/AstraZeneca, Astellas Pharma Inc|Pfizer, Arvinas Inc., Arcus Biosciences, Aptevo Therapeutics, Antigen Express, Amgen, Advaxis, Advanced Accelerator Applications (A Novartis Company), Abbvie, AB Science, and others
- Roche is investigating ipatasertib as part of a combination with Zytiga (abiraterone acetate; Johnson & Johnson/AstraZeneca) in asymptomatic or mildly symptomatic, previously untreated metastatic castration-resistant prostate cancer patients.
- DCVAC is an autologous immunotherapy manufactured from a patient’s white blood cells. It is composed of autologous Polyinosinic-Polycytidylic activated dendritic cells pulsed with killed LNCaP prostate cancer cell line. Sotio is currently leading following trials for the treatment of Metastatic prostate cancer.
For further information, refer to the detailed Metastatic Prostate Cancer Unmet Needs, Metastatic Prostate Cancer Market Drivers, and Metastatic Prostate Cancer Market Barriers, click here for Metastatic Prostate Cancer Ongoing Clinical Trial Analysis
Metastatic Prostate Cancer Emerging Drugs Profile
- FP-001: Foresee Pharmaceuticals
FP-001 is a long-acting gonadotropin releasing hormone (GnRH) agonist being developed as Leuprolide Mesylate for Injectable Suspension. It is under development by Foresee Pharmaceuticals and ScinoPharm Joint Venture and is currently in Phase III stage for the treatment of Prostate Cancer. The drug candidate is being developed in different dosage formulations and depending on them, they are in different stages of development.
- Relugolix: Myovant Biosciences
Relugolix (Pre-registration) is the Myovant’s lead product candidate and is an orally available small molecule, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively binds to and blocks the GnRH receptor in the anterior pituitary gland, which both prevents GnRH binding to the GnRH receptor and inhibits the secretion and release of both luteinizing hormone (LH) and follicle stimulating hormone (FSH).
- Atezolizumab: Genentech
Atezolizumab (Tecentriq, Phase III) is a novel, anti-PDL1 targeted prescription cancer immunotherapy. It is monoclonal antibody derived from the Chinese hamster ovary cells by recombinant DNA technology. Atezolizumab works by binding to PD-L1 receptor expressed on tumor cells and tumor-infiltrating immune cells and thereby leads to the prevention of binding of PD-L1 receptor to other proteins namely as B7.1 and PD-1. This process leads to the release of PD-1/ PD-L1 mediated inhibition of the immune response, and also causes the activation of anti-tumor immune response without inducing the antibody dependent cellular cytotoxicity (ADCC). As stated by the company, this mode of action may eliminate the “stop sign” that gives the signals to inactivate T-cells. Tecentriq may also affect normal cells.
- Darolutamide: Bayer
Darolutamide (Phase III) is an orally administered second generation androgen receptor (AR) antagonist that has a unique chemical structure designed to block the growth of cancer cells through binding to the AR with high affinity and inhibiting the receptor function. In preclinical studies, darolutamide and its main circulating metabolite are active also in known AR mutants (ex W742L, F877L), and have been found to have negligible blood-brain barrier penetration.
- DCVAC/PCa: Sotio
DCVAC is an autologous immunotherapy manufactured from a patient’s white blood cells. It is composed of autologous Polyinosinic-Polycytidylic activated dendritic cells pulsed with killed LNCaP prostate cancer cell line. Sotio is currently leading following trials for the treatment of Metastatic prostate cancer-
Phase III: Randomized, Double Blind, Multicenter, Parallel-group, Phase III Study to Evaluate Efficacy and Safety of DCVAC/PCa Versus Placebo in Men with Metastatic Castration Resistant Prostate Cancer Eligible for 1st Line Chemotherapy
Phase I/II: Clinical Trial to Evaluate the Safety and Immune Activation of the Combination of DCVAC/PCa, and ONCOS-102, in Men with Advanced Metastatic Castration-resistant Prostate Cancer
Request a sample and discover the recent advances in Metastatic Prostate Cancer Ongoing Clinical Trial Analysis and Medications, click here @ Metastatic Prostate Cancer Treatment Landscape
Metastatic Prostate Cancer Pipeline Therapeutics Assessment
There are approx. 90+ key companies which are developing the therapies for Metastatic Prostate Cancer. The companies which have their Metastatic Prostate Cancer drug candidates in the most advanced stage, i.e. Pre-registration phase include, Foresee Pharmaceuticals and Myovant Biosciences.
Dive deep into rich insights for drugs for Metastatic Prostate Cancer Pipeline, click here @ Metastatic Prostate Cancer Unmet Needs and Analyst Views
Scope of the Metastatic Prostate Cancer Pipeline Report
- Coverage- Global
- Metastatic Prostate Cancer Companies- Zenith Epigenetics, WntResearch, Veru Inc., VasGene Therapeutics, ValiRx, Vaccitech, Ultimovacs ASA, Trovagene, Tracon, Tmunity Therapeutics, Tesaro, and others.
- Metastatic Prostate Cancer Pipeline Therapies- Enzalutamide, Sunitinib, Metformin, Anti-OX40, Cyclophosphamide, Cabazitaxel, and others.
- Metastatic Prostate Cancer Pipeline Therapies- Product Type, Molecule Type, Mechanism of Action, Route of Administration
Got Queries? Find out the related information on Metastatic Prostate Cancer Mergers and acquisitions, Metastatic Prostate Cancer Licensing Activities @ Metastatic Prostate Cancer Emerging Drugs, and Recent Trends
Table of Content
- Introduction
- Executive Summary
- Metastatic Prostate Cancer: Overview
- Pipeline Therapeutics
- Therapeutic Assessment
- Metastatic Prostate Cancer – DelveInsight’s Analytical Perspective
- In-depth Commercial Assessment
- Metastatic Prostate Cancer Collaboration Deals
- Late Stage Products
- Atezolizumab: Genentech
- Darolutamide: Bayer
- Drug profiles in the detailed report…..
- Mid Stage Products
- Recombinant EphB4-HSA Fusion Protein: Vasgene Therapeutics
- AZD4635: AstraZeneca PLC
- Drug profiles in the detailed report…..
- Early Stage Products
- Gallium-68-P16 093: Five Eleven Pharma
- ABBV-744: Abbvie
- Drug profiles in the detailed report…..
- Pre-clinical and Discovery Stage Products
- EPI 7386: ESSA Pharma
- Drug profiles in the detailed report…..
- Inactive Products
- Metastatic Prostate Cancer Key Companies
- Metastatic Prostate Cancer Key Products
- Metastatic Prostate Cancer- Unmet Needs
- Metastatic Prostate Cancer- Market Drivers and Barriers
- Metastatic Prostate Cancer- Future Perspectives and Conclusion
- Metastatic Prostate Cancer Analyst Views
- Metastatic Prostate Cancer Key Companies
- Appendix
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