(Albany, US) DelveInsight has launched a new report on “Hemophilia B Pipeline Insight, 2020”.
“Hemophilia B Pipeline Insight, 2020” report by DelveInsight outlays comprehensive insights of present clinical development scenario and growth prospects across the Hemophilia B market. A detailed picture of the Hemophilia B pipeline landscape is provided, which includes the disease overview and Hemophilia B treatment guidelines.
The assessment part of the report embraces in-depth Hemophilia B commercial assessment and clinical assessment of the Hemophilia B pipeline products from the pre-clinical developmental phase to the marketed phase. In the report, a detailed description of the drug is proffered including mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Hemophilia B collaborations, licensing, mergers and acquisition, funding, designations, and other product-related details.
Key companies covered:
- Novo Nordisk
- CSL Behring
- Bioverativ Therapeutics
- UniQure
- Pfizer
- Freeline Therapeutics
- And Many Others
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Drugs covered:
- Rebinyn
- Idelvion
- Alprolix
- Etranacogene dezaparvovec (AMT-061)
- Fidanacogene elaparvovec
- FLT180a
- And Many Others
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Report Highlights:
- The Hemophilia B report provides an overview of therapeutic pipeline activity and therapeutic assessment of the products by development stage, product type, route of administration, molecule type, and MOA type for Hemophilia B across the complete product development cycle, including all clinical and nonclinical stages.
- It comprises of detailed profiles of Hemophilia B therapeutic products with key coverage of developmental activities, including technology, collaborations, licensing, mergers and acquisition, funding, designations and other product-related details
- Detailed Hemophilia B research and development progress and trial details, results wherever available, are also included in the pipeline study.
- Coverage of dormant and discontinued pipeline projects along with the reasons if available across Hemophilia B.
Hemophilia B is a genetic disorder caused by missing or defective Factor IX clotting protein.With the lack of this, the blood cannot clot properly to control bleeding like hemophilia A, it is also inherited and is caused by a spontaneous genetic mutation in one-third of the cases. Individuals with hemophilia B do not bleed faster than unaffected individuals, they bleed longer.
It is caused by an inherited X-linked recessive trait, with the defective gene located on the X chromosome. A male who has a hemophilia gene on his X chromosome will have hemophilia. When a female has a haemophilia gene on only one of her X chromosomes, she is a “hemophilia carrier” and can pass the gene to her children.
Sometimes carriers have low levels of clotting factor and have symptoms of hemophilia, including bleeding. Clotting factors are proteins in the blood that work together with platelets to stop or control bleeding.
The main signs and symptoms of hemophilia are excessive bleeding and easy bruising. The child may suffer from recurrent nose bleeds, blood loss from small cuts, long-term bleeding in the mouth from bites, or after removal of a tooth, on-and-off bleeding from a cut or injury, bleeding within the skin or muscle and soft tissue that causes build-up of blood in the area.
The diagnosis of hemophilia B is established in individuals with low factor IX clotting activity. Identification of a hemizygous F9 pathogenic variant on molecular genetic testing in a male proband confirms the diagnosis.
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Table of Contents:
1. Report Introduction
2. Hemophilia B
2.1. Overview
2.2. History
2.3. Hemophilia B Symptoms
2.4. Causes
2.5.Pathophysiology
2.6. Hemophilia B Diagnosis
2.6.1. Diagnostic Guidelines
3. Hemophilia B Current Treatment Patterns
3.1. Hemophilia B Treatment Guidelines
4. Hemophilia B – DelveInsight’s Analytical Perspective
4.1. In-depth Commercial Assessment
4.1.1. Hemophilia B companies collaborations, Licensing, Acquisition -Deal Value Trends
4.1.1.1. Assessment Summary
4.1.2. Hemophilia B Collaboration Deals
4.1.2.1. Company-Company Collaborations (Licensing / Partnering) Analysis
4.1.2.2. Company-University Collaborations (Licensing / Partnering) Analysis
4.1.2.3. Hemophilia B Acquisition Analysis
5. Therapeutic Assessment
5.1. Clinical Assessment of Pipeline Drugs
5.1.1. Assessment by Phase of Development
5.1.2. Assessment by Product Type (Mono / Combination)
5.1.2.1. Assessment by Stage and Product Type
5.1.3. Assessment by Route of Administration
5.1.3.1. Assessment by Stage and Route of Administration
5.1.4. Assessment by Molecule Type
5.1.4.1. Assessment by Stage and Molecule Type
5.1.5. Assessment by MOA
5.1.5.1. Assessment by Stage and MOA
5.1.6. Assessment by Target
5.1.6.1. Assessment by Stage and Target
6. Hemophilia B Late Stage Products (Phase-III)
7. Hemophilia B Mid Stage Products (Phase-II)
8. Early Stage Products (Phase-I)
9. Pre-clinical Products and Discovery Stage Products
10. Inactive Products
11. Dormant Products
12. Hemophilia B Discontinued Products
13. Hemophilia B Product Profiles
13.1. Drug Name: Company
13.1.1. Product Description
13.1.1.1. Product Overview
13.1.1.2. Mechanism of action
13.1.2. Research and Development
13.1.2.1. Clinical Studies
13.1.3. Product Development Activities
13.1.3.1. Collaboration
13.1.3.2. Agreements
13.1.3.3. Acquisition
13.1.3.4. Patent Detail
13.1.4. Tabulated Product Summary
13.1.4.1. General Description Table
Detailed information in the report?
14. Hemophilia B Key Companies
15. Hemophilia B Key Products
16. Dormant and Discontinued Products
16.1. Dormant Products
16.1.1. Reasons for being dormant
16.2. Discontinued Products
16.2.1. Reasons for the discontinuation
17. Hemophilia B Unmet Needs
18. Hemophilia B Future Perspectives
19. Hemophilia B Analyst Review
20. Appendix
21. Report Methodology
21.1. Secondary Research
21.2. Expert Panel Validation
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About DelveInsight
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