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Fabry Disease Market to Register Stunning Growth During the Forecast Period (2023-2032) – DelveInsight | Key Companies – Sigilon, AVROBIO, uniQure, Resverlogix, Codexis, Canbridge, Eleva GmbH

Fabry Disease Market to Register Stunning Growth During the Forecast Period (2023-2032) - DelveInsight | Key Companies - Sigilon, AVROBIO, uniQure, Resverlogix, Codexis, Canbridge, Eleva GmbH
Delveinsight Business Research LLP

As per DelveInsight, the Fabry Disease Market is anticipated to evolve immensely in the coming years owing to the increasing prevalence of the disease and the launch of promising emerging pipeline therapies with new mechanisms of action.

DelveInsight’s “Fabry Disease Market Insights, Epidemiology, and Market Forecast 2032” report delivers an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the Fabry Disease market size, share, trends, and growth opportunities in the seven major markets (7MM) (i.e., the United States, EU4 (Germany, Spain, Italy, France), the United Kingdom and Japan).

The report covers emerging Fabry Disease drugs, current treatment practices, market share of individual therapies, and current & forecasted market size from 2019 to 2032. It also evaluates the current Fabry Disease treatment practice/algorithm, key drivers & barriers impacting the market growth, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market. 

Fabry Disease Market

Fabry Disease: An Overview

Fabry disease is an inherited lysosomal storage disease caused by a nonfunctional or partially functional enzyme, alpha-galactosidase A (α-Gal A). Decreased activity of α-Gal A in lysosomes results in the accumulation of enzyme substrates (Gb3 and lyso-Gb3) which cause cellular damage in tissues throughout the body.

Symptoms include pain that spreads through the body (called a Fabry crisis), gastrointestinal complications, headaches, impaired sweating, vertigo, and hearing impairment. It was once thought that Fabry disease only affected males; females were thought of as only “carriers.” However, it is now known that both men and women can get Fabry disease, though it may manifest differently depending on gender.

Despite being X-linked, heterozygous women may experience all the signs and symptoms of Fabry disease that are seen in men; however, compared with hemizygous males, signs and symptoms of Fabry disease in women typically emerge at an older age and with less severity.

Fabry Disease Market Key Facts

  • The Fabry Disease market size in the seven major markets was nearly USD 1,200 million in 2020.

  • The prevalent population of Fabry Disease in the 7MM countries was estimated to be around 13,000 in 2020.

  • Several new therapies are under research, including new forms of ERT, substrate reduction therapy, mRNA therapy, and gene therapy, to address the current challenges in the treatment.

  • Some of the key players in the Fabry Disease Market include Protalix Biotherapeutics, Sanofi Genzyme, Idorsia Pharmaceuticals, Avrobio, Sangamo Therapeutics, 4D Molecular Therapeutics, Freeline Therapeutics, and several others.

Fabry Disease Market

The market outlook section of the report helps to build a detailed comprehension of the historical, current, and forecasted market size by analyzing the impact of current and emerging Fabry Disease pipeline therapies. It also thoroughly assesses the Fabry Disease market drivers & barriers, unmet needs, and emerging technologies set to impact the market dynamics.

The report gives complete detail of the market trend for each marketed Fabry Disease drug and mid & late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, their Mechanism of Action (MOA), Route of Administration (ROA), molecule types, competition with other therapies, brand value, and their impact on the market.

Fabry Disease Epidemiology Assessment 

The epidemiology section provides insights into the historical, current, and forecasted Fabry Disease epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted Fabry Disease epidemiology trends by exploring numerous studies and research. The epidemiology section also provides a detailed analysis of diagnosed and prevalent patient pools, future trends, and views of key opinion leaders. 

The Report Covers the Fabry Disease Epidemiology, Segmented as –

  • Prevalent Cases of Fabry Disease in the 7MM [2019–2032]

  • Age-specific Cases of Fabry Disease in the 7MM [2019–2032]

  • Gender-specific Cases of Fabry Disease in the 7MM [2019–2032]

  • Diagnosed Cases of Fabry Disease in the 7MM [2019–2032]

  • Phenotype-specific cases of Fabry Disease the 7MM [2019–2032

  • Treated Cases of Fabry Disease in the 7MM [2019–2032]

Fabry Disease Drugs Uptake and Pipeline Development Activities

The drug uptake section focuses on the uptake rate of potential drugs recently launched in the Fabry Disease market or expected to be launched during the study period. The analysis covers the Fabry Disease market uptake by drugs, patient uptake by therapies, and sales of each drug. Moreover, the therapeutics assessment section helps understand the market dynamics by drug sales, the most rapid drug uptake, and the reasons behind the maximal use of particular drugs. Additionally, it compares the Fabry Disease drugs based on their sale and market share.

The report also covers the Fabry Disease pipeline development activities. It provides valuable insights about different therapeutic candidates in various stages and the key Fabry Disease companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

Learn How the Fabry Disease Market Will Evolve and Grow by 2032 @

Fabry Disease Therapeutics Analysis

Treatment of Fabry disease (FD) consists of enzyme replacement therapy (ERT), oral chaperone therapy, and adjunctive treatment, including ACE inhibitors or angiotensin receptor blockers, antiplatelet drugs, and analgesics. Studies have shown that ERT can delay, but not always prevent, some of the clinical complications of FD. Currently, the effective management of FD requires a multidisciplinary approach with comprehensive therapy of intravenously administered ERT or chaperone therapy and adjunct therapies, including lifestyle modifications and prophylactic medications.

To further improve the treatment scenario, several major pharma and biotech companies are developing therapies for Fabry Disease. Currently, Protalix Biotherapeutics is leading the therapeutics market with its Fabry Disease drug candidates in the most advanced stage of clinical development.

Fabry Disease Companies Actively Working in the Therapeutics Market Include

  • Idorsia Pharmaceuticals

  • Protalix

  • Sanofi Genzyme

  • Sangamo Therapeutics

  • 4D Molecular Therapeutics

  • Resverlogix Corp


  • Freeline Therapeutics

  • Ozmosis Research Inc.

  • CellGenTech, Inc.

  • uniQure

  • Codexis

  • Canbridge

  • Eleva GmbH

  • MP6 therapeutics

  • Amicus therapeutics

  • Sigilon Therapeutics

And Many Others

Emerging and Marketed Fabry Disease Therapies Covered in the Report Include:

  • Pegunigalsidase Alfa: Protalix Biotherapeutics

  • Venglustat: Sanofi

  • 4D 310: 4D Molecular Therapeutics

  • ST-920: Sangamo Therapeutics

  • FLT190: Freeline Therapeutics

And Many More

The Report Covers the In-depth Assessment of the Emerging Drugs & Key Companies. Download the Sample Report to Learn More @

Table of Content (TOC)

1. Key Insights

2. Executive Summary 

3. Fabry Disease Competitive Intelligence Analysis

4. Fabry Disease Market Overview at a Glance

5. Fabry Disease Disease Background and Overview

6. Fabry Disease Patient Journey

7. Fabry Disease Patient Population and Epidemiology Trends (In the US, EU5, and Japan)

8. Fabry Disease Treatment Algorithm, Current Treatment, and Medical Practices

9. Fabry Disease Unmet Needs

10. Key Endpoints of Fabry Disease Treatment

11. Fabry Disease Marketed Therapies

12. Fabry Disease Emerging Drugs and Latest Therapeutic Advances

13. Fabry Disease Seven Major Market Analysis

14. Attribute Analysis

15. Fabry Disease Market Outlook (In US, EU5, and Japan)

16. Fabry Disease Companies Active in the Market

17. Fabry Disease Access and Reimbursement Overview

18. KOL Views on the Fabry Disease Market

19. Fabry Disease Market Drivers

20. Fabry Disease Market Barriers

21. Appendix

22. DelveInsight Capabilities

23. Disclaimer

*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.

Download the Sample PDF to Learn More About the Key Offerings of the Report @


About DelveInsight

DelveInsight is a leading Business Consultant and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance.


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