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Peripheral Nerve Injuries Market, Size, Share, Trends, Epidemiology Forecast till 2030

Peripheral Nerve Injuries Market, Size, Share, Trends, Epidemiology Forecast till 2030

DelveInsight Business Research LLP

DelveInsight’s ‘Peripheral Nerve Injuries Market Insights, Epidemiology, and Market Forecast – 2030’ report delivers an in-depth understanding of the PNI, historical and forecasted epidemiology as well as the PNI market trends in the United States, EU5(Germany, France, Italy, Spain, and the United Kingdom) and Japan.

Peripheral Nerve Injuries comprises of various reversible and irreversible nerve impairments due to traumatic nerve injuries. People with Peripheral Nerve Injuries can experience severe pain, tingling, burning sensation, or loss of sensation in the affected part of the body.  

The diagnosis of PNI in acute trauma cases is often ignored. Most of the nerve injuries are of mixed grade, and there is no diagnostic test to discriminate between Sunderland grades II and IV except histological examination.

A better understanding of the pathophysiology of PNI is crucial to ensure proper management. More in-depth studies on the pathophysiology of PNI and targeted research of the effective treatments are required to improve poor outcomes of the patients and reduce the related morbidity of PNI.

There is an immediate need for better selective therapy for the treatment of PNI, yet the drugs currently in the development are quite less and mostly comprise of the nerve repair devices. The approved products include conduits and nerve grafts. No drug or biologics is yet approved that have the potential to increase nerve repair and regeneration. There are only a few drugs anticipated to get launched by 2030.

Peripheral Nerve Injuries Market Insight

Peripheral Nerve Injuries market size in 7MM in 2017 was USD 2,182.82 million 

Peripheral Nerve Injuries Market Drivers

  • High incidence of nerve injuries
  • Availability of technologically advanced nerve repair and regeneration products
  • Research and Development

Peripheral Nerve Injuries Market Barriers

  • Delayed and underdiagnosis
  • Lack of epidemiological studies
  • Limited understanding of the pathophysiology of Peripheral Nerve Injuries and repair
  • Lack of approved therapies and weak clinical pipeline 

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Table of contents

1. Key Insights

2. Executive Summary of Peripheral Nerve Injuries (PNI)

3. Peripheral Nerve Injuries Market Overview at a Glance

3.1. Market Share (%) Distribution of PNI in 2017

3.2. Market Share (%) Distribution of PNI in 2030

4. Disease Background and Overview: Peripheral Nerve Injuries (PNI)

4.1. Introduction

4.2. Peripheral nerves and their Injuries

4.3. Causes of PNI

4.4. Symptoms of PNI

4.5. Grading of PNI

4.6. Pathophysiology of Nerve Injury

4.7. Mechanism of PNI

4.8. Diagnosis of PNI

4.9. PNI guidelines (NHS)

5. Case Reports

5.1. Case presentation for peripheral nerve neuropraxia (trauma)

5.2. A case report of a long-term abandoned torn lingual nerve injury repaired by collagen nerve graft induced by lower third molar extraction

5.3. Peripheral nerve injury associated with a sub dermal contraceptive implant: illustrative cases and systematic review of literature

6. Epidemiology and Patient Population

6.1. Key Findings

6.2. KOL Views

6.3. Epidemiology Methodology

6.4. Total Number of Annual Peripheral Nerve Injuries (PNI) in the 7MM

6.5. Total Annual Number of PNI by extremities in the 7MM

6.6. Total Number of PNI Surgeries Performed in the 7MM

7. United States Epidemiology

7.1. Assumptions and Rationale

7.2. Total Number of Annual Peripheral Nerve Injuries in the United States

7.3. Total Annual Number of PNI by extremities in the United States

7.4. Total Number of PNI Surgeries Performed in the United States

8. EU5 Epidemiology

8.1. Germany Epidemiology

8.1.1. Assumptions and Rationale

8.1.2. Total Number of Annual Peripheral Nerve Injuries in Germany

8.1.3. Total Annual Number of PNI by extremities in Germany

8.1.4. Total Number of PNI Surgeries Performed in Germany

8.2. France Epidemiology

8.2.1. Assumptions and Rationale

8.2.2. Total Number of Annual Peripheral Nerve Injuries in France

8.2.3. Total Annual Number of PNI by extremities in France

8.2.4. Total Number of PNI Surgeries Performed in France

8.3. Italy Epidemiology

8.3.1. Assumptions and Rationale

8.3.2. Total Number of Annual Peripheral Nerve Injuries in Italy

8.3.3. Total Annual Number of PNI by extremities in Italy

8.3.4. Total Number of PNI Surgeries Performed in Italy

8.4. Spain Epidemiology

8.4.1. Assumptions and Rationale

8.4.2. Total Number of Annual Peripheral Nerve Injuries in Spain

8.4.3. Total Annual Number of PNI by extremities in Italy

8.4.4. Total Number of PNI Surgeries Performed in Spain

8.5. United Kingdom Epidemiology

8.5.1. Assumptions and Rationale

8.5.2. Total Number of Annual Peripheral Nerve Injuries in the United Kingdom

8.5.3. Total Annual Number of PNI by extremities in the United Kingdom

8.5.4. Total Number of PNI Surgeries Performed in the United Kingdom

9. Japan Epidemiology

9.1. Assumptions and Rationale

9.2. Total Number of Annual Peripheral Nerve Injuries in Japan

9.3. Total Annual Number of PNI by extremities in Japan

9.4. Total Number of PNI Surgeries Performed in Japan

10. Treatment

10.1. Surgical Approaches

10.2. Non-surgical therapeutic approaches for nerve recovery

10.3. Transcutaneous electrical nerve stimulation (TENS)

11. Unmet needs

12. Marketed Drugs

12.1. Key Cross

12.2. Nerbridge: Toyobo

12.2.1. Product Description

12.2.2. Other Developmental Activities

12.2.3. Safety and Efficacy

12.2.4. Product Profile

12.3. Neurolac and Neurolac Thin Wall (TW): Polyganics

12.3.1. Product Description

12.3.2. Regulatory Milestones

12.3.3. Other Developmental Activities

12.3.4. Clinical Development

12.3.5. Safety and Efficacy

12.3.6. Product Profile

12.4. Avance Nerve Graft: Axogen Corporation

12.4.1. Product Description

12.4.2. Regulatory Milestones

12.4.3. Other Developmental Activities

12.4.4. Clinical Development

12.4.5. Safety and Efficacy

12.4.6. Product Profile

13. Emerging Drugs

13.1. NTX-001: Neuraptive Therapeutics

13.1.1. Product Description

13.1.2. Other Developmental Activities

13.1.3. Clinical Development

13.1.4. Product Profile

13.2. SilkBridge: Silk Biomaterials

13.2.1. Product Description

13.2.2. Other Developmental Activities

13.2.3. Clinical Development

13.2.4. Safety and Efficacy

13.2.5. Product Profile

13.3. CelGro: Orthocell Limited

13.3.1. Product Description

13.3.2. Other Developmental Activities

13.3.3. Clinical Development

13.3.4. Safety and Efficacy

13.3.5. Product Profile

14. Peripheral Nerve Injuries (PNI): 7MM Market Analysis

14.1. Key Findings

14.2. Market Methodology

14.3. Market Size of Peripheral Nerve Injuries (PNI) in the 7MM

14.4. Market Size of Peripheral Nerve Injuries (PNI) by Techniques in the 7MM

15. Seven Major Market Outlook

16. United States Market Size

16.1. United States Market Size

16.1.1. Total market size of Peripheral Nerve Injuries (PNI) in the United States

16.1.2. Market Size of Peripheral Nerve Injuries (PNI) by Techniques in the US

17. EU-5 Market Size

17.1. Germany Market Size

17.1.1. Total Market size of Peripheral Nerve Injuries (PNI) in Germany

17.1.2. Market Size of Peripheral Nerve Injuries (PNI) by Techniques in Germany

17.2. France Market Size

17.2.1. Total Market size of Peripheral Nerve Injuries (PNI) in France

17.2.2. Market Size of Peripheral Nerve Injuries (PNI) by Techniques in France

17.3. Italy Market Size

17.3.1. Total Market size of Peripheral Nerve Injuries (PNI) in Italy

17.3.2. Market Size of Peripheral Nerve Injuries (PNI) by Techniques in Italy

17.4. Spain Market Size

17.4.1. Total Market size of Peripheral Nerve Injuries (PNI) in Spain

17.4.2. Market Size of Peripheral Nerve Injuries (PNI) by Techniques in Spain

17.5. United Kingdom Market Size

17.5.1. Total Market size of Peripheral Nerve Injuries (PNI) in the United Kingdom

17.5.2. Market Size of Peripheral Nerve Injuries (PNI) by Techniques in the UK

18. Japan Market Size

18.1. Japan Market Size

18.1.1. Total Market size of Peripheral Nerve Injuries (PNI) in Japan

18.1.2. Market Size of Peripheral Nerve Injuries (PNI) by Techniques in Japan

19. Market Drivers

20. Market Barriers

21. SWOT Analysis

22. Reimbursement and Market Access

23. Appendix

23.1. Bibliography

23.2. Report Methodology

24. DelveInsight Capabilities

25. Disclaimer

26. About DelveInsight

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